HELPING THE OTHERS REALIZE THE ADVANTAGES OF PRO33

Inhibition of focal adhesion kinase (FAK) rescued SERT function in synapses of KI mice, demonstrating that constitutive active FAK signaling downstream from the Pro32Pro33 integrin αvβ3 suppresses SERT action. Our reports detect a fancy regulation of 5-HT homeostasis and behaviors by integrin αvβ3, revealing an essential job for integrins in mo